Interactions between particulate matter and bacteria during cowshed PM2.5-induced respiratory injury initiates GBP2/Caspase-11/NLRP3-mediated intracellular bacterial defense and pyroptosis

Interactions between particulate matter and bacteria during cowshed PM2.5-induced respiratory injury initiates GBP2/Caspase-11/NLRP3-mediated intracellular bacterial defense and pyroptosis

IntroductionFine particulate matter (PM2.5) is an important factor in the induction of a variety of respiratory diseases and associated cellular damage. The composition of PM2.5 in the animal farm environments is complex, which poses a significant threat to the respiratory health of both workers and...

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Bibliographic Details
Main Authors: Xiaohui Du, Zhenhua Ma, Yize Sun, Yunna Jia, Xiqing Zhang, Cuizhu Zhao, Xiaojun Liang, Xiuzhen Yu, Yunhang Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Veterinary Science
Subjects:
the animal farm environment
PM2.5
Pasteurella multocida
respiratory injury
GBP2
NLRP3
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1631913/full
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https://www.frontiersin.org/articles/10.3389/fvets.2025.1631913/full

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