Development of a reliable method for human triple-negative breast cancer organotypic culture: Improving imaging and genomic studies in 3D cultures

Development of a reliable method for human triple-negative breast cancer organotypic culture: Improving imaging and genomic studies in 3D cultures

Triple-negative breast cancer (TNBC) is highly aggressive and lacks targeted therapies, posing a major challenge in oncology. Traditional two-dimensional (2D) cell cultures fail to capture the tumor microenvironment’s complexity, whereas three-dimensional (3D) cultures provide a more accurate model...

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Main Authors: Mercedes Olvera-Valencia, Verónica Garcia-Castillo, Rosalío Ramos-Payan, Maribel Aguilar-Medina, Samuel Trujano-Camacho, Alejandro López-Saavedra, Laurence A. Marchat, Cesar López-Camarillo, Ronen Sumagin, Eloy Pérez-Yepez, Carlos Pérez-Plasencia
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314251326668
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https://doi.org/10.1177/20417314251326668

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