Rap1 overexpression boosts triterpenoid saponin production in yeast by enhancing precursor supply and heterologous gene expression

Abstract Background Metabolic engineering to increase the supply of precursors, such as 2,3-oxidosqualene (OSQ), and manipulate heterologous biosynthetic pathways through the strategic overexpression of multiple genes is promising for increasing the microbial production of triterpenoid saponins. How...

Full description

Saved in:
Bibliographic Details
Main Authors: Ji-Young Byun, Thi Thuy Nguyen, Byung-Kwan Cho, Soo-Hoon Park, Sun-Chang Kim
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-025-02667-3
Tags: Add Tag
No Tags, Be the first to tag this record!