Preliminary Study on Lutetium-177 and Gold Nanoparticles: Apoptosis and Radiation Enhancement in Hepatic Cancer Cell Line

Preliminary Study on Lutetium-177 and Gold Nanoparticles: Apoptosis and Radiation Enhancement in Hepatic Cancer Cell Line

This study investigates a novel approach toward enhancing the efficacy of Lutetium-177 (Lu-177) radiopharmaceutical therapy by combining it with gold nanoparticles (AuNPs) in the HepG2 hepatic cancer cell line. Lu-177, known for its effective β radiation, also emits gamma rays at energies (113 keV a...

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Bibliographic Details
Main Authors: Maria Anthi Kouri, Anastasios Georgopoulos, George E. Manios, Eirini Maratou, Aris Spathis, Sofia Chatziioannou, Kalliopi Platoni, Efstathios P. Efstathopoulos
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Current Issues in Molecular Biology
Subjects:
gold nanoparticles
Lutetium-177
radionuclide therapy
molecular therapy
HepG2 cancer cell line
gold nanospheres
Online Access:https://www.mdpi.com/1467-3045/46/11/727
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