Mental Health and Quality of Life in Patients with Untreated Unruptured Intracranial Aneurysms: A Systematic Review and Meta-Analysis of 417,152 Patients with Trial Sequential Analysis

<b>Introduction:</b> Unruptured intracranial aneurysms (UIAs) can induce psychological stress, leading to anxiety, depression, and impaired quality of life (QoL). Most studies on this topic are limited by small sample sizes, cross-sectional designs, and a focus on treated rather than unt...

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Main Authors: Plamen Penchev, Kiril Ivanov, Daniela Milanova-Ilieva, Lyubomir Gaydarski, Kiril Kostov, Nikola Boyadzhiev, Petar-Preslav Petrov, Patrice Mehandzhiev, Remzi Hyusein, Vladislav Velchev, Ilko Ilyov, Valentin Kuzmanov, Gergana Dzhikova, Desislava Dobreva, Liliana Toptchiyska, Vasilena Dimitrova, Victoria Petrova, Svetoslav Yorov, Pavel Stanchev, Martin Gyulbaharov, Noor Husain, Nikolai Ramadanov
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Brain Sciences
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Online Access:https://www.mdpi.com/2076-3425/15/7/764
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