Disruption of hindgut microbiome homeostasis promotes postpartum energy metabolism disorders in dairy ruminants by inhibiting acetate-mediated hepatic AMPK-PPARA axis
Abstract Background Postpartum energy metabolism disorders pose a significant challenge to the health and productivity of dairy ruminants, yet their underlying pathogenesis remains poorly understood. The critical role of the gut microbiota in regulating host metabolic processes via the “gut-liver ax...
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| Main Authors: | Shuo Wang, Fanlin Kong, Xinyue Zhang, Dongwen Dai, Chen Li, Zhijun Cao, Yajing Wang, Wei Wang, Shengli Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Microbiome |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40168-025-02150-6 |
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