Genome-wide profiling of DNA repair proteins in single cells

Genome-wide profiling of DNA repair proteins in single cells

Abstract Accurate repair of DNA damage is critical for maintenance of genomic integrity and cellular viability. Because damage occurs non-uniformly across the genome, single-cell resolution is required for proper interrogation, but sensitive detection has remained challenging. Here, we present a com...

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Main Authors: Kim L. de Luca, Pim M. J. Rullens, Magdalena A. Karpinska, Sandra S. de Vries, Agnieszka Gacek-Matthews, Lőrinc S. Pongor, Gaëlle Legube, Joanna W. Jachowicz, A. Marieke Oudelaar, Jop Kind
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54159-4
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https://doi.org/10.1038/s41467-024-54159-4

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