Replisomes restrict SMC translocation in vivo

Abstract Structural maintenance of chromosomes (SMC) complexes organize genomes by extruding DNA loops, while replisomes duplicate entire chromosomes. These essential molecular machines must collide frequently in every cell cycle, yet how such collisions are resolved in vivo remains poorly understoo...

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Bibliographic Details
Main Authors: Qin Liao, Hugo B. Brandão, Zhongqing Ren, Xindan Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62596-y
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