Methylglyoxal-induced RNA modifications decrease RNA stability and translation and are associated with type 2 diabetes
Objectives: Methylglyoxal (MG), a reactive aldehyde generated as a byproduct of glucose and lipid metabolism, is known to modify nucleic acids and proteins, altering their structure and function. While MG-induced DNA and protein adducts have been extensively studied and associated with type 2 diabet...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | Molecular Metabolism |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877825000936 |
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