B-cell epitope peptide immunotherapy alleviates chitin-binding protein-induced type 2 airway inflammation in a Blomia tropicalis-murine model

B-cell epitope peptide immunotherapy alleviates chitin-binding protein-induced type 2 airway inflammation in a Blomia tropicalis-murine model

Abstract Background Peptide immunotherapy (PIT) offers a safe and effective treatment with minimal side effects. This study aims to identify B-cell epitopes of a novel allergen from Blomia tropicalis (B. tropicalis), specifically the Chitin-binding domain type 2 (ChtBD2) protein, and evaluate the th...

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Bibliographic Details
Main Authors: Jiale Zhang, Wenting Luo, YuBao Cui, Baoqing Sun
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Respiratory Research
Subjects:
B-cell epitopes
Peptide immunotherapy
Blomia tropicalis
Chitin-binding domain type 2 (ChtBD2) protein
Artificial intelligence
Online Access:https://doi.org/10.1186/s12931-025-03207-8
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https://doi.org/10.1186/s12931-025-03207-8

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