Pharmacokinetic Profile of Two Active Dipyrone Metabolites, 4-Methylaminoantipyrine (MAA) and 4-Aminoantipyrine (AA), Following Intravenous Administration in Dogs: A Preliminary Study

Pharmacokinetic Profile of Two Active Dipyrone Metabolites, 4-Methylaminoantipyrine (MAA) and 4-Aminoantipyrine (AA), Following Intravenous Administration in Dogs: A Preliminary Study

This study aimed to determine the pharmacokinetic profile of the active dipyrone metabolites, 4-methylaminoantipyrine and 4-aminoantipyrine, following intravenous administration in dogs. Eleven mixed-breed dogs received a 25 mg·kg<sup>−1</sup> dipyrone dose and blood samples were collect...

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Main Authors: Andressa N. Mouta, Kathryn N. Arcoverde, Naftáli S. Fernandes, Yanna D. B. Passos, Caio V. A. de Oliveira, Robson A. Honorato, Gabriel Araujo-Silva, Valéria V. de Paula
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Animals
Subjects:
analgesia
chromatography
metamizole
metabolism
Online Access:https://www.mdpi.com/2076-2615/15/11/1666
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