Assessment of basal TSPO expression and [18F]DPA-714 biodistribution in healthy mice and post-ischemic brain using PET imaging

Assessment of basal TSPO expression and [18F]DPA-714 biodistribution in healthy mice and post-ischemic brain using PET imaging

Positron emission tomography (PET) is an important tool in preclinical studies in small animals, providing real-time insights into biochemical, metabolic, physiological, and functional processes. PET imaging also enables the assessment of biological responses and biodistribution of novel radiolabel...

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Main Authors: Brígida Gomes de Almeida Schirmer, Juliana de Oliveira Silva, Douglas Boniek Silva Navarro, João Vitor Reis Marques, Mariana Duarte de Souza, Ianara Pereira Silva, Juliana Batista da Silva, Carlos Malamut
Format: Article
Language:English
Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 2025-04-01
Series:Brazilian Journal of Radiation Sciences
Subjects:
MicroPET
[18F]DPA-714
biodistribution
TSPO
Online Access:https://bjrs.org.br/revista/index.php/REVISTA/article/view/2812
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https://bjrs.org.br/revista/index.php/REVISTA/article/view/2812

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