Common Mechanisms Underlying Opioid Tolerance and Dependence and Neuropathic Pain: Role of Metabotropic Glutamate Receptors

It has been suggested that opioid tolerance and dependence share common mechanisms with neuropathic pain. This short review deals with the role of glutamate and glutamate receptors in opioid tolerance and dependence, and neuropathic pain. Particular attention is given to the role of metabotropic glu...

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Bibliographic Details
Main Author: Marian E Fundytus
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2000/437256
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