Inhibiting Autophagy by Chemicals During SCAPs Osteodifferentiation Elicits Disorganized Mineralization, While the Knock-Out of <i>Atg5/7</i> Genes Leads to Cell Adaptation

Inhibiting Autophagy by Chemicals During SCAPs Osteodifferentiation Elicits Disorganized Mineralization, While the Knock-Out of <i>Atg5/7</i> Genes Leads to Cell Adaptation

SCAPs (Stem Cells from Apical Papilla), derived from the apex of forming wisdom teeth, extracted from teenagers for orthodontic reasons, belong to the MSCs (Mesenchymal Stromal Cells) family. They have multipotent differentiation capabilities and are a potentially powerful model for investigating st...

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Bibliographic Details
Main Authors: Damien Le Nihouannen, Claudine Boiziau, Sylvie Rey, Nicole Agadzhanian, Nathalie Dusserre, Fabrice Cordelières, Muriel Priault, Helene Boeuf
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
mesenchymal stem cells
SCAPs
canonical autophagy
alternative autophagy
bafilomycin A1
verteporfin
Online Access:https://www.mdpi.com/2073-4409/14/2/146
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