Effect of host microenvironment and bacterial lifestyles on antimicrobial sensitivity and implications for susceptibility testing

Abstract Bacterial infections remain a major global health issue, with antimicrobial resistance (AMR) worsening the crisis. However, treatment failure can occur even when bacteria show antibiotic susceptibility in diagnostic tests. We explore factors such as phenotypic resilience, bacterial lifestyl...

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Bibliographic Details
Main Authors: Ramon Garcia-Maset, Victoria Chu, Nicholas Yuen, Dalia Blumgart, Jenny Yoon, Benjamin O. Murray, Amelia A. Joseph, Jennifer L. Rohn
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-025-00113-3
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