Alleviating cognitive impairments in bipolar disorder with a novel DTI-guided multimodal neurostimulation protocol: a double-blind randomized controlled trial

Alleviating cognitive impairments in bipolar disorder with a novel DTI-guided multimodal neurostimulation protocol: a double-blind randomized controlled trial

Abstract Background Traditional neuromodulation strategies show promise in enhancing cognitive abilities in bipolar disorder (BD) but remain suboptimal. This study introduces a novel multimodal neurostimulation (MNS) protocol to improve therapeutic outcomes. Methods The novel MNS protocol used indiv...

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Bibliographic Details
Main Authors: Minmin Wang, Hetong Zhou, Xiaomei Zhang, Qianfeng Chen, Qiqi Tong, Qiai Han, Xudong Zhao, Dandan Wang, Jianbo Lai, Hongjian He, Shaomin Zhang, Shaohua Hu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medicine
Subjects:
Diffusion tensor imaging
Transcranial alternating current stimulation
Repetitive transcranial magnetic stimulation
Electric field
Individualization
Online Access:https://doi.org/10.1186/s12916-025-04174-z
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https://doi.org/10.1186/s12916-025-04174-z

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