Expanded CD8+CD38+ T Cell Population in Patients With Systemic Lupus Erythematosus Is Linked to Increased Infection Rates: A Prospective Study

Objective One of the leading causes of morbidity and mortality among patients with systemic lupus erythematosus (SLE) is infections. The expression of the ectonucleotidase CD38 on the surface of CD8+ T cells has been linked to compromised cytotoxic function. The aim of this prospective study was to...

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Bibliographic Details
Main Authors: Jose Rubio, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O'Connell, George C. Tsokos, Vasileios Kyttaris
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:ACR Open Rheumatology
Online Access:https://doi.org/10.1002/acr2.11725
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