Genetically druggable targets for MAPK-activated colorectal cancer by a two-sample mendelian randomization analysis

Abstract Colorectal cancer (CRC) is a significant worldwide health issue, ranking second in women and third in men. Predictions estimate a rise to 2.5 million cases by 2035, with CRC being the fourth deadliest cancer due to delayed diagnosis and the scarcity of effective treatment options. Over 60%...

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Bibliographic Details
Main Authors: Yuxuan Zhou, Yunlong Ding, Bangyue Xu, Hongyang Fei, Zheng Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-82567-5
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