Whole Blood Metabolomic Profiling of Mice with Tacrolimus-Induced Chronic Nephrotoxicity: NAD<sup>+</sup> Depletion with Salvage Pathway Impairment

Whole Blood Metabolomic Profiling of Mice with Tacrolimus-Induced Chronic Nephrotoxicity: NAD<sup>+</sup> Depletion with Salvage Pathway Impairment

Tacrolimus (TAC)-induced chronic nephrotoxicity (TAC nephrotoxicity) is a serious issue for long-term graft survival in kidney transplantation. However, the pathophysiology of TAC nephrotoxicity remains unclear. In this study, we analyzed whole blood samples from mice that developed TAC nephrotoxici...

Full description

Saved in:
Bibliographic Details
Main Authors: Sho Nishida, Tamaki Ishima, Daiki Iwami, Ryozo Nagai, Kenichi Aizawa
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antioxidants
Subjects:
tacrolimus (TAC)
TAC nephrotoxicity
NAD<sup>+</sup>
metabolomics
chronic kidney disease biomarkers
ADMA
Online Access:https://www.mdpi.com/2076-3921/14/1/62
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2076-3921/14/1/62

Similar Items