The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast

The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast

The Target of Rapamycin kinase Complex 1 (TORC1) regulates cell growth and metabolism in eukaryotes. Previous studies have shown that, in Saccharomyces cerevisiae, nitrogen and amino acid signals activate TORC1 via the highly conserved small GTPases, Gtr1/2, and the phosphatidylinositol 3-phosphate...

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Bibliographic Details
Main Authors: Jacob H Cecil, Cristina M Padilla, Austin A Lipinski, Paul Langlais, Xiangxia Luo, Andrew P Capaldi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
Subjects:
TORC1
protein kinase
nutrient
Gtr1/2
Pib2
Online Access:https://elifesciences.org/articles/94628
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https://elifesciences.org/articles/94628

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