Brain-Death in Rats Increases Neutrophil Extracellular Trap Formation in Donor Organs

During brain-death, increased numbers of neutrophils are recruited to organs as part of the inflammatory response. In the organ microenvironment, the recruited neutrophils may release neutrophil extracellular traps (NETs) through interaction with various pro-inflammatory stimuli, contributing to bra...

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Bibliographic Details
Main Authors: Maryna Van Zyl, Roberto Armstrong Junior, Petra Ottens, Harry Van Goor, Mia-Jeanne Van Rooy, Ton Lisman, Henri G. D. Leuvenink, Jan-Luuk Hillebrands
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Transplant International
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Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14223/full
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