HMGB1 as an emerging key modulator of bone remodeling: a narrative review

Abstract Bone is a dynamic tissue that undergoes microdamage and requires remodeling to replace old bone matrix. This process demands a tight coupling between bone resorption and bone formation. Aberrant internal environment can decouple these processes, reducing bone mass and compromising mechanica...

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Bibliographic Details
Main Authors: Jun Tang, Ming Li, Lin Huang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-025-04543-8
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