Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism

Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism

Abstract To investigate the role and mechanisms of gut microbiota in hyperuricemia-induced renal injury, we established renal failure models using unilateral nephrectomized mice. After four weeks of adenine and potassium oxalate-supplemented diet, probiotic intervention was administered. Renal patho...

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Main Authors: Ping Liu, Ping Hu, Meiping Jin, Weiqian Sun, Jiajun Wu, Yuyan Tang, Danye Shi, Ting Xie, Yijing Tong, Lusheng Huang, Dongliang Zhang, Hui Zheng, Xudong Xu, Haidong He
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Microbiology
Subjects:
Compound probiotics
Uric acid nephropathy
Metabolomics
Amino acid metabolism
Online Access:https://doi.org/10.1186/s12866-025-04012-5
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https://doi.org/10.1186/s12866-025-04012-5

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