Lassa virus persistence with high viral titers following experimental infection in its natural reservoir host, Mastomys natalensis

Abstract Lassa virus (LASV) outbreaks in West Africa pose a significant public health threat. We investigated the infection phenotype and transmission (horizontal and vertical) of LASV strain Ba366 in its natural host, Mastomys natalensis. Here we analyze viral RNA levels in body fluids, virus titer...

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Bibliographic Details
Main Authors: Chris Hoffmann, Susanne Krasemann, Stephanie Wurr, Kristin Hartmann, Elisa Adam, Sabrina Bockholt, Jonas Müller, Stephan Günther, Lisa Oestereich
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53616-4
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