The repair effect of α-ketoglutarate combined with mesenchymal stem cells on osteoarthritis via the hedgehog protein pathway

Objective: Mesenchymal stem cell (MSC) therapy represents a promising treatment strategy for osteoarthritis (OA). Nevertheless, the therapeutic efficacy of MSCs may be attenuated under conditions of cellular senescence or when the available clinical quantity is insufficient. α-Ketoglutarate (AKG) ex...

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Bibliographic Details
Main Authors: Liyan Li, Han Shen, Li Lu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-03-01
Series:Journal of Holistic Integrative Pharmacy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2707368825000032
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