Ouabain Counteracts Retinal Ganglion Cell Death Through Modulation of BDNF and IL-1 Signaling Pathways

Ouabain Counteracts Retinal Ganglion Cell Death Through Modulation of BDNF and IL-1 Signaling Pathways

<b>Background:</b> Ouabain is a steroid hormone that binds to the sodium pump (Na<sup>+</sup>, K<sup>+</sup>-ATPase) at physiological (nanomolar) concentrations, activating different signaling pathways. This interaction has been shown to prevent the axotomy-induce...

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Main Authors:	Amanda Candida da Rocha Oliveira, Camila Saggioro Figueiredo, Ícaro Raony, Juliana Salles Von-Held-Ventura, Marcelo Gomes Granja, Thalita Mázala-de-Oliveira, Vinícius Henrique Pedrosa-Soares, Aline Araujo dos Santos, Elizabeth Giestal-de-Araujo
Format:	Article
Language:	English
Published:	MDPI AG 2025-01-01
Series:	Brain Sciences
Subjects:	brain-derived neurotrophic factor cytokine growth factor steroid hormone interleukin-1β matrix metalloproteinase-9
Online Access:	https://www.mdpi.com/2076-3425/15/2/123
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