Uptake of DU145 and LNCaP prostate cancer cell line derived extracellular vesicles is inversely correlated with blood–brain barrier integrity in vitro
Abstract Background Tumor-derived small extracellular vesicles (sEVs) have been implicated in changes of the blood–brain barrier (BBB) during pre-metastatic niche formation. Although it was postulated that sEVs can traverse the highly restrictive BBB via transcytosis—data mostly based on the indirec...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Fluids and Barriers of the CNS |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12987-025-00680-7 |
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