Ectopic expression of the mitochondrial protein COXFA4L3 in human sperm acrosome and its potential application in the selection of male infertility treatments

Ectopic expression of the mitochondrial protein COXFA4L3 in human sperm acrosome and its potential application in the selection of male infertility treatments

Abstract Purpose Spermatogenesis requires a large amount of energy, which is primarily produced by the mitochondrial electron transfer chain. Mitochondrial dysfunction affects male infertility, suggesting a relationship between the electron transfer chain and male infertility. COXFA4L3 (C15ORF48) is...

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Main Authors: Yusuke Fujisawa, Sayaka Kikuchi, Fujino Kuba, Kosei Oishi, Soushi Murayama, Tomoya Sugiyama, Reiji Tokito, Hiroe Ueno, Shin‐ichi Kashiwabara, Yasushi Yumura, Yasuyuki Kurihara
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Reproductive Medicine and Biology
Subjects:
cytochrome c oxidase
electron transport chain
male infertility
mitochondria
sperm
Online Access:https://doi.org/10.1002/rmb2.12602
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https://doi.org/10.1002/rmb2.12602

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