Characterizing meiotic chromosomes' structure and pairing using a designer sequence optimized for Hi‐C

Characterizing meiotic chromosomes' structure and pairing using a designer sequence optimized for Hi‐C

Abstract In chromosome conformation capture experiments (Hi‐C), the accuracy with which contacts are detected varies due to the uneven distribution of restriction sites along genomes. In addition, repeated sequences or homologous regions remain indistinguishable because of the ambiguities they intro...

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Bibliographic Details
Main Authors: Héloïse Muller, Vittore F Scolari, Nicolas Agier, Aurèle Piazza, Agnès Thierry, Guillaume Mercy, Stéphane Descorps‐Declere, Luciana Lazar‐Stefanita, Olivier Espeli, Bertrand Llorente, Gilles Fischer, Julien Mozziconacci, Romain Koszul
Format: Article
Language:English
Published: Springer Nature 2018-07-01
Series:Molecular Systems Biology
Subjects:
chromatin loop
cohesin
meiosis
Rec8
synthetic chromosome
Online Access:https://doi.org/10.15252/msb.20188293
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https://doi.org/10.15252/msb.20188293

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