Glycolysis Changes in Alloreactive Memory B Cells in Highly Sensitized Kidney Transplant Recipients Undergoing Desensitization Therapy

Glycolysis Changes in Alloreactive Memory B Cells in Highly Sensitized Kidney Transplant Recipients Undergoing Desensitization Therapy

Despite the growing use of desensitization strategies, hyperimmune patients remain at high risk of antibody-mediated rejection suggesting that, even when donor-specific antibodies (DSA) are effectively depleted, anti-donor specific B cells persist. We included 10 highly sensitized recipients that un...

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Bibliographic Details
Main Authors: Johan Noble, Lara Cabezas, Aurelie Truffot, Lucile Dumolard, Thomas Jouve, Paolo Malvezzi, Lionel Rostaing, Céline Dard, Philippe Saas, Paolo Cravedi, Zuzana Macek-Jilkova
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Transplant International
Subjects:
donor-specific antibody
desensitization
kidney transplantation
metabolism
memory B cells
glycolysis
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13029/full
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https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13029/full

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