SIMULTANEOUS DETERMINATION OF AMINOTRIAZOLE AND TRIAZOLOPYRIMIDINONE - SUBSTRATE AND INTERMEDIATE IN THE SYNTHESIS OF «TRIAZIDE» BY HPLC

SIMULTANEOUS DETERMINATION OF AMINOTRIAZOLE AND TRIAZOLOPYRIMIDINONE - SUBSTRATE AND INTERMEDIATE IN THE SYNTHESIS OF «TRIAZIDE» BY HPLC

Method of simultaneous determination of aminotriazole and triazolopyrimidinone using HPLC with UV-detection was developed. For best chromatographic performance Zorbax NH2 amino phase column (Agilent Technologies, USA) was selected. The applicability of the developed method for providing technologica...

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Bibliographic Details
Main Authors: A. V. Baklykov, A. A. Tumashov, S. K. Kotovskaya, E. N. Ulomskiy, G. L. Rusinov, V. L. Rusinov, O. N. Chupahin, V. N. Charushin
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
aminotriazole
triazolopyrimidinone
«triazide»
hplc
validation
Online Access:https://www.pharmjournal.ru/jour/article/view/421
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