Astrocyte to neuron reprogramming with NeuroD1 for repair in canine stroke

Stroke affects hundreds of thousands of people each year and leads to neuronal damage and often long term disabilities. This study served as an exploratory study investigating astrocyte to neuron reprogramming as a potential treatment for ischemic stroke using a canine model to assess anatomical and...

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Bibliographic Details
Main Authors: Isaac H. Clark, Zachary Roushdy, Dilmareth Natera-Rodriguez, Kevin Sun, Olivia Erlanson, Shaimaa Khedr, Walter C. Low, Andrew W. Grande
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Stroke
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Online Access:https://www.frontiersin.org/articles/10.3389/fstro.2025.1602076/full
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