Brain-derived neurotrophic factor and cytokines as predictors of cognitive impairment in adolescent and young adult cancer patients receiving chemotherapy: a longitudinal study

Abstract Background Inflammatory signaling is linked with cancer-related cognitive impairment (CRCI), potentially through modulation of brain-derived neurotrophic factor (BDNF) expression. Here, we evaluate associations between plasma cytokines and BDNF and their relationship with cognition in a lon...

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Bibliographic Details
Main Authors: Julia Trudeau, Ding Quan Ng, Michael Sayer, Chia Jie Tan, Yu Ke, Raymond J. Chan, Alexandre Chan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-025-14430-3
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