Unveiling the anti-inflammatory potential of RF16, an interleukin 8-derived therapeutic peptide in macrophages
Abstract Background Interleukin 8 (IL-8, also known as CXCL-8) regulates inflammation and breast cancer formation by activating its cognate receptor CXCR1/2. In our previous study, a RF16 peptide, derived from the IL-8 binding region of CXCR1/2, was synthesized to inhibit IL-8-stimulated and LPS-ind...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Journal of Inflammation |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12950-025-00454-w |
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