Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing
Abstract Optical imaging plays a central role in the field of biomedicine, but it suffers from the light scattering of tissues. The research group from Stanford University has reported a counterintuitive observation that strongly absorbing molecules could achieve optical transparency in live animals...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2025-01-01
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| Series: | Light: Science & Applications |
| Online Access: | https://doi.org/10.1038/s41377-024-01675-z |
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| _version_ | 1841559059367460864 |
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| author | Tingting Yu Dan Zhu |
| author_facet | Tingting Yu Dan Zhu |
| author_sort | Tingting Yu |
| collection | DOAJ |
| description | Abstract Optical imaging plays a central role in the field of biomedicine, but it suffers from the light scattering of tissues. The research group from Stanford University has reported a counterintuitive observation that strongly absorbing molecules could achieve optical transparency in live animals, providing a new insight for understanding tissue optical clearing. It empowers scientists to leverage optical imaging techniques for in vivo observation of a wide range of deep-seated structures and activities. |
| format | Article |
| id | doaj-art-48ee0762446c40bbbe79bdbe4830b880 |
| institution | Kabale University |
| issn | 2047-7538 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Light: Science & Applications |
| spelling | doaj-art-48ee0762446c40bbbe79bdbe4830b8802025-01-05T12:46:48ZengNature Publishing GroupLight: Science & Applications2047-75382025-01-011411310.1038/s41377-024-01675-zStrongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearingTingting Yu0Dan Zhu1Britton Chance Center for Biomedical Photonics-MoE Key Laboratory for Biomedical Photonics, Advanced Biomedical Imaging Facility-Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and TechnologyBritton Chance Center for Biomedical Photonics-MoE Key Laboratory for Biomedical Photonics, Advanced Biomedical Imaging Facility-Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and TechnologyAbstract Optical imaging plays a central role in the field of biomedicine, but it suffers from the light scattering of tissues. The research group from Stanford University has reported a counterintuitive observation that strongly absorbing molecules could achieve optical transparency in live animals, providing a new insight for understanding tissue optical clearing. It empowers scientists to leverage optical imaging techniques for in vivo observation of a wide range of deep-seated structures and activities.https://doi.org/10.1038/s41377-024-01675-z |
| spellingShingle | Tingting Yu Dan Zhu Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing Light: Science & Applications |
| title | Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing |
| title_full | Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing |
| title_fullStr | Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing |
| title_full_unstemmed | Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing |
| title_short | Strongly absorbing molecules make tissue transparent: a new insight for understanding tissue optical clearing |
| title_sort | strongly absorbing molecules make tissue transparent a new insight for understanding tissue optical clearing |
| url | https://doi.org/10.1038/s41377-024-01675-z |
| work_keys_str_mv | AT tingtingyu stronglyabsorbingmoleculesmaketissuetransparentanewinsightforunderstandingtissueopticalclearing AT danzhu stronglyabsorbingmoleculesmaketissuetransparentanewinsightforunderstandingtissueopticalclearing |