Association between C677T variant of methylene tetrahydrofolate reductase and hypospadias risk in Algeria

Association between C677T variant of methylene tetrahydrofolate reductase and hypospadias risk in Algeria

Background. Hypospadias, a congenital condition characterized by the urethral opening being on the underside of the penis, has received limited attention in its association with the MTHFR C677T variant. Given the crucial role of folate metabolism in embryonic development, and the involvement of the...

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Bibliographic Details
Main Authors: Rania Laouar, Djalila Chellat-Rezgoune, Meroua Horchi, Rayene Achou, Brahim Djoudi, Souhem Touabti, Yacine Benhizia, Karima Sifi
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2025-07-01
Series:The Turkish Journal of Pediatrics
Subjects:
hypospadias
MTHFR
C677T
risk factors
folic acid
polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)
Online Access:https://turkjpediatr.org/article/view/6049
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https://turkjpediatr.org/article/view/6049

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