Prevalence and clinical relavance of germline mutations in Chinese patients with pancreatic cancer

Prevalence and clinical relavance of germline mutations in Chinese patients with pancreatic cancer

Abstract Introduction The prevalence and clinical significance of germline sequence variations in unselected Chinese pancreatic cancer (PC) patients remain underexplored. Methods This retrospective study analyzed PC patients (not selected for age or family history) who underwent germline cancer pred...

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Bibliographic Details
Main Authors: Yu Jiang, Dan Li, Yang Liu, Jiejie Qin, Hao Chen, Jun Zhang, Yijin Gu, Baiyong Shen, Jiabin Jin
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
Subjects:
Pancreatic cancer
Germline mutation
Cancer predisposition gene
Therapeutically actionable germline variant
Genotype directed therapy
Online Access:https://doi.org/10.1186/s12964-025-02281-1
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https://doi.org/10.1186/s12964-025-02281-1

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