Endogenous epoxygenases are modulators of monocyte/macrophage activity.

<h4>Background</h4>Arachidonic acid is metabolized through three major metabolic pathways, the cyclooxygenase, lipoxygenase and CYP450 enzyme systems. Unlike cyclooxygenase and lipoxygenases, the role of CYP450 epoxygenases in monocyte/macrophage-mediated responses is not known.<h4>...

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Bibliographic Details
Main Authors: Jonas Bystrom, Jessica A Wray, Mary C Sugden, Mark J Holness, Karen E Swales, Timothy D Warner, Matthew L Edin, Darryl C Zeldin, Derek W Gilroy, David Bishop-Bailey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0026591&type=printable
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