Modeling ALS with Patient-Derived iPSCs: Recent Advances and Future Potentials

Amyotrophic lateral sclerosis (ALS) is a terminal complex neurodegenerative disease, with 10–15% of cases being familial and the majority being sporadic with no known cause. There are no animal models for the 85–90% of sporadic ALS cases. More creative, sophisticated models of ALS disease are requir...

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Bibliographic Details
Main Authors: Ladan Dawoody Nejad, Erik P. Pioro
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/15/2/134
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