Functional characterization of DPP4 and FcRn as receptor and coreceptor for classical human astroviruses in Caco-2 cells.

Classical human astroviruses (HAstV) are a global cause of viral gastroenteritis, particularly in children and immunocompromised individuals. Despite their clinical significance, the biology of HAstV remains poorly understood. In particular, the identification of cellular receptors and coreceptors h...

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Main Authors: Catalina Aguilera-Flores, María Del Pilar Valencia-Morales, Tomás López, Joaquín Moreno-Contreras, Adam Lentz, Marco A Espinoza, Rebecca M DuBois, Susana López, Carlos F Arias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013316
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