Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial

Dapagliflozin effect on functional mitral regurgitation and myocardial remodelling: The DEFORM trial

Abstract Aims Functional mitral regurgitation (FMR) is associated with adverse outcomes in patients with heart failure, and current guideline‐directed medical therapy (GDMT) offers limited efficacy in managing FMR. This study aims to evaluate the therapeutic impact of the sodium‐glucose cotransporte...

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Main Authors: Zhuoshan Huang, Rui Fan, Shaozhao Zhang, Junlin Zhong, Yiquan Huang, Peihan Xie, Shanshan Yin, Xiaomin Ye, Xinghao Xu, Rihua Huang, Zhenyu Xiong, Yue Guo, Menghui Liu, Yifen Lin, Suhua Li, Xiaoxian Qian, Jinlai Liu, Xiaodong Zhuang, Xinxue Liao
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:ESC Heart Failure
Subjects:
Dapagliflozin
Functional mitral regurgitation
Myocardial remodelling
Online Access:https://doi.org/10.1002/ehf2.15296
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https://doi.org/10.1002/ehf2.15296

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