Transcriptional Profiling Underscores the Role of Preprocurement Allograft Metabolism and Innate Immune Status on Outcomes in Human Liver Transplantation

Objective:. The adverse effects of ischemia-reperfusion injury (IRI) remain a principal barrier to a successful outcome after lifesaving orthotopic liver transplantation (OLT). Gene expression during different phases of IRI is dynamic and modified by individual exposures, making it attractive for id...

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Bibliographic Details
Main Authors: Joohyun Kim, MD, PhD, Michael T. Zimmermann, PhD, Angela J. Mathison, PhD, Gwen Lomberk, PhD, Raul Urrutia, MD, Johnny C. Hong, MD
Format: Article
Language:English
Published: Wolters Kluwer Health 2024-06-01
Series:Annals of Surgery Open
Online Access:http://journals.lww.com/10.1097/AS9.0000000000000444
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