Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study

Drug-resistant epilepsy associated with peripheral complement decreases and sex-specific cytokine imbalances: a pilot study

Abstract Drug-resistant epilepsy (DRE) presents significant challenges in treatment and management. While seizure-related alterations in peripheral immune players are increasingly recognized, the involvement of the immune complement system remains insufficiently explored in DRE. We studied complemen...

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Bibliographic Details
Main Authors: Nicole Pinzon-Hoyos, Yibo Li, Monnie McGee, Nicholas P. Poolos, Nicola Marchi, Amy L. Brewster
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Refractory epilepsy
Complement system
Cytokines
Sex dimorphism
Seizures
Online Access:https://doi.org/10.1038/s41598-025-88654-5
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https://doi.org/10.1038/s41598-025-88654-5

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