Signaling Centers Drive Brachyury Dynamics and Lineage Commitment in mESC Aggregates

ABSTRACT Stem cell‐based models of embryogenesis have exploded in popularity, resulting in protocols with overlapping use of some reagents and differential use of others. As such, the precise contributions of individual signaling molecules, such as Chiron and BMP4, applied to whole or part of aggreg...

Full description

Saved in:
Bibliographic Details
Main Authors: A. Rabeling, M. Goolam
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:FASEB BioAdvances
Subjects:
Online Access:https://doi.org/10.1096/fba.2024-00216
Tags: Add Tag
No Tags, Be the first to tag this record!