Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei

Background Pseudomyxoma peritonei (PMP) is a rare, slow-growing abdominal cancer with no efficacious treatment options in non-resectable and recurrent cases. Otherwise, rare activating mutations in the GNAS oncogene are remarkably frequent in PMP and the mutated gene product, guanine nucleotide-bind...

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Bibliographic Details
Main Authors: Ben Davidson, Kjersti Flatmark, Annette Torgunrud, Karianne G Fleten, Hedvig V Juul, Nadia Mensali, Christin Lund-Andersen, Else Marit Inderberg
Format: Article
Language:English
Published: BMJ Publishing Group 2021-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/10/e003109.full
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