Application of an organoid-based model to explore Helicobacter pylori–human gastric epithelium interaction in vitro

Helicobacter pylori infection causes histopathologic changes in gastric epithelial cells, resulting in conditions such as gastritis, gastric ulcers, and ultimately, gastric cancer. To date, various experimental models, including cell lines and animal studies, have been employed to investigate these...

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Bibliographic Details
Main Authors: Byeong Min Yu, So Dam Lee, Bo Ram Hwang, Ji Seon Kim, Sungsook Yu, Ki Taek Nam, Yong Chan Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1572244/full
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