Efficacy and safety of low-dose TBI combined MAC regimen for HSCT in high-risk AML patients with active disease

Efficacy and safety of low-dose TBI combined MAC regimen for HSCT in high-risk AML patients with active disease

Background The management of high-risk acute myeloid leukaemia (AML) remains challenging, highlighting the need for innovative conditioning strategies beyond current regimens.Methods In the present single-arm study, a FACT regimen comprised of low-dose total body irradiation (TBI) with fludarabine,...

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Bibliographic Details
Main Authors: Can Chen, Yang Fan, Ying Xu, Yaping Xie, Kuang Chen, Xilian Huang, Daquan Gao, Junfeng Tan, Lirong Liu, Shenxian Qian, Pengfei Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
Subjects:
Acute myeloid leukaemia
allogeneic hematopoietic stem cell transplantation
conditioning regimen
prognosis
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2024.2446692
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https://www.tandfonline.com/doi/10.1080/07853890.2024.2446692

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