Integrating spatial and single-cell transcriptomics to characterize mouse long bone fracture healing process

Abstract Bone fracture healing is a dynamic process that relies on coordinated cellular interactions for effective tissue regeneration. We employ optimized spatial transcriptomics to delineate the locations and interactions of the involved cell types within a mouse femur fracture model on Day 0 befo...

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Bibliographic Details
Main Authors: Hanning Wang, Xuan He, Mingjie Ma, Tianxu Dou, Yulong Wei, Danielle Rux, Ling Qin, Yan Yang, Yue Zhu, Lutian Yao
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08316-0
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