Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice

Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice

Abstract The histaminergic system plays a key role in modulating learning and memory, wakefulness, and energy balance. Histamine H3 receptors constitutively inhibit the synthesis and release of histamine and other neurotransmitters. Therefore, H3 receptor inverse agonists/antagonists increase the sy...

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Bibliographic Details
Main Authors: Sentaro Kaita, Yoshikazu Morishita, Kenta Kobayashi, Hiroshi Nomura
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Brain
Subjects:
Histamine
H3 receptor
Somatosensory cortex
Synchronized activity
Spontaneous activity
Online Access:https://doi.org/10.1186/s13041-024-01165-8
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https://doi.org/10.1186/s13041-024-01165-8

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