Screening, identification, and experimental validation of SUMOylation biomarkers in Parkinson’s disease

Screening, identification, and experimental validation of SUMOylation biomarkers in Parkinson’s disease

Abstract Background Parkinson’s disease (PD) is a common neurodegenerative disorder. The role of protein post-translational modifications (PTMs), especially small ubiquitin-like modifier (SUMO) conjugation (SUMOylation), in PD pathogenesis remains unclear. This study aimed to investigate the relatio...

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Bibliographic Details
Main Authors: Yifo Wei, Xinning Zhang, Rui Zuo, Wenxin Dang, Lu Chen, Fan Liu, Jia Yao, Weizheng Ran, Zhigang Chen, Xiaoyan Wang, Furong Lv, Yue Yu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Hereditas
Subjects:
Parkinson's disease
SUMOylation
Biomarker
Machine learning
SUMO3
SEH1L
Online Access:https://doi.org/10.1186/s41065-025-00525-1
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https://doi.org/10.1186/s41065-025-00525-1

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